Recent Publications


Molecular Diagnostics

  1. Chim SSC, Jin S, Lee TY, Lun FMF, Lee WS, Chan LYS, Jin Y, Yang N, Tong YK, Leung TY, Lau TK, Ding C, Chiu RWK, Lo YMD: Systematic search for placental DNA-methylation markers on chromosome 21: toward a maternal plasma-based epigenetic test for fetal trisomy 21. Clin Chem 2008, 54:500-11
  2. Chim SSC, Shing TKF, Hung EC, Leung TY, Lau TK, Chiu RWK, Lo YMD: Detection and characterization of placental microRNAs in maternal plasma. Clin Chem 2008, 54:482-90
  3. Tsang JCH, Charoenkwan P, Chow KCK, Jin Y, Wanapirak C, Sanguansermsri T, Lo YMD, Chiu RWK: Mass spectrometry-based detection of hemoglobin E mutation by allele-specific base extension reaction. Clin Chem 2007, 53:2205-9
  4. Tong YK, Chiu RWK, Leung TY, Ding C, Lau TK, Leung TN, Lo YMD: Detection of restriction enzyme-digested target DNA by PCR amplification using a stem-loop primer: application to the detection of hypomethylated fetal DNA in maternal plasma. Clin Chem 2007, 53:1906-14
  5. Lo YMD, Chiu RWK: Prenatal diagnosis: progress through plasma nucleic acids. Nat Rev Genet 2007, 8:71-7
  6. Lo YMD, Tsui NBY, Chiu RWK, Lau TK, Leung TN, Heung MMS, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C: Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat Med 2007, 13:218-23
  7. Lo YMD, Lun FMF, Chan KCA, Tsui NBY, Chong KC, Lau TK, Leung TY, Zee BC, Cantor CR, Chiu RWK: Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci U S A 2007, 104:13116-21
  8. Chow KCK, Chiu RWK, Tsui NBY, Ding C, Lau TK, Leung TN, Lo YMD: Mass spectrometric detection of an SNP panel as an internal positive control for fetal DNA analysis in maternal plasma. Clin Chem 2007, 53:141-2
  9. Chiu RWK, Chim SSC, Wong IH, Wong CS, Lee WS, To KF, Tong JH, Yuen RKC, Shum AS, Chan JK, Chan LYS, Yuen JW, Tong YK, Weier JF, Ferlatte C, Leung TN, Lau TK, Lo KW, Lo YMD: Hypermethylation of RASSF1A in human and rhesus placentas. Am J Pathol 2007, 170:941-50
  10. Tong YK, Ding C, Chiu RWK, Gerovassili A, Chim SSC, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo YMD: Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations. Clin Chem 2006, 52:2194-202
  11. Chiu RWK, Lui WB, Cheung MC, Kumta N, Farina A, Banzola I, Grotti S, Rizzo N, Haines CJ, Lo YMD: Time profile of appearance and disappearance of circulating placenta-derived mRNA in maternal plasma. Clin Chem 2006, 52:313-6
  12. Chan KCA, Ding C, Gerovassili A, Yeung SW, Chiu RWK, Leung TN, Lau TK, Chim SSC, Chung GTY, Nicolaides KH, Lo YMD: Hypermethylated RASSF1A in maternal plasma: A universal fetal DNA marker that improves the reliability of noninvasive prenatal diagnosis. Clin Chem 2006, 52:2211-8
  13. Chim SSC, Tong YK, Chiu RWK, Lau TK, Leung TN, Chan LYS, Oudejans CB, Ding C, Lo YMD: Detection of the placental epigenetic signature of the maspin gene in maternal plasma. Proc Natl Acad Sci U S A 2005, 102:14753-8

Gastrointestinal Diseases

  1. Sung JJY. Current management of peptic ulcer bleeding. Nature Clinical Practice Gastro & Hepatol 2006, 3:24-32
  2. Leung WK, Chan MC, To KF, man EP, Ng EK, Chu ES, Lau JYW, Lin SR, Sung JJY: H. pylori genotypes and cytokines gene polymorphisms influence the development of gastric intestinal metaplasia in a Chinese population. Am J Gastroenterol 2006, 101(4):714-20
  3. Sung JJY, Chan HLY. HBV-ISS (Dynavax) Curr Opin Mol Ther 2006, 8:150-5
  4. He ML, Zheng BJ, Chen Y, Wong KL, Huang JD, Lin MC, Peng Y, Yuen KY, Sung JJY, Kung HF. Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus. FEBS Let 2006, 580:241-20
  5. Leong RW, Lawrance IC, Chow DK, To KF, Lau JYW, Wu JCY, Leung WK, Chan FKL, Sung JJY. Association of Intestinal Granulomas with Smoking, Phenotype, and Serology in Chinese Patients with Crohn's Disease. Am J Gastroenterol 2006 May, 101(5):1024-9
  6. Lau JYW, Leow CK, Fung TM, Suen BY, Yu LM, Lai PB, Lam YH, Ng EK, Lau WY, Chung SS, Sung JJY. Cholecystectomy or gallbladder in situ after endoscopic sphincterotomy and bile duct stone removal in chinese patients. Gastroenterology 2006, 130:96-103
  7. Chan HLY, Sung JJY. Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 2006, 153-61
  8. Lai LH, Wong GL, Chow DK, Lau JY, Sung JJY, Leung WK. Inter-observer variations on interpretation of capsule endoscopies. Eur J Gastroenterol Hepatol 2006, 18: 283-6
  9. Chan MH, Chan PK, Griffith JF, Chan IH, Lit LC, Wong CK, Antonio GE, Liu EY, Hui DS, Suen MW, Ahuja AT, Sung JJY, Lam CW. Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy. Pathology 2006, 38: 229-35
  10. Chiu PW, Hu B, Lau JYW, Sun LC, Sung JJY, Chung SCS. Endoscopic plication of massively bleeding peptic ulcer by using the Eagle Claw VII device: a feasibility study in a porcine model. Gastrointest Endosc 2006,63: 681-5
  11. Yu CM, Wong RS, Wu EB, Kong SL, Wong J, Yip GW, Soo YO, Chiu ML, Chan YS, Hui D, Lee N, Wu A, Leung CB, Sung JJY. Cardiovascular complications of severe acute respiratory syndrome. Postgrad Med J 2006, 82:140-4
  12. Roccia F, Agrati C, Castilletti C, Bordi L, Gioia C, Horejsh D, Ippolito G, Chan PK, Hui DS, Sung JJY Capobianchi MR, Malkovsky M. Anti-Severe Acute Respiratory Syndrome Coronavirus Immune Responses: The Role Played by V gamma 9V delta 2 T Cells. J Infect Dis 2006, 193:1244-9
  13. Hui AY, Leung WK, Yuen Chan HL, Chan FK, Yin Go MY, Chan KK, Tang BD, Hong Chu ES, Sung JJY. Effect of celecoxib on experimental liver fibrosis in rat. Liver Int 2006, 26:126-36
  14. He ML, Lin C, Tong K, Xu B, Sung JJY, Kung HF, Lee SS. Absence of CYP2B6 promoter -82T>C mutation in Chinese as an additional factor for slow metabolism of drugs commonly used in infections. Eur J Clin Pharmacol 2006, 62:585-6
  15. Pang RT, Poon TC, Chan KCA, Lee NL, Chiu RWK, Tong YK, Wong RM, Chim SSC, Ngai SM, Sung JJ, Lo YMD: Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome. Clin Chem 2006, 52:421-9
  16. Leung WK, Ng EKW, Lam CCH, Chan KF, Chan WY, Auyeung ACM, Wu JCY, Ching JYL, Lau JYW, Sung JJY. Helicobacter pylori infection in first degree relatives of Chinese gastric cancer patients. Scan J Gastroenterol 2006, 41:274-9
  17. Lai LH, Wong GLH, Chow DKL, Lau JYW, Sung JJY, Leung WK. Long term follow up on patients with obscure gastrointestinal bleeing after negative capsule endoscopy. Am J Gastroenterol 2006, 101:1224-8
  18. Leung WK, Sung JJY. Chemoprevention of gastric cancer. Eur J Gastroenterol Hepatol 2006, 18:867-71
  19. Bian ZX, Wu TX, Liu L, Miao JX, Wong HF, Song L, Sung JJY. Effectiveness of the Chinese herbal formula TongXieYaoFang for irritable bowel syndrome. J Complementary Alternative Med 2006, 12:401-7
  20. Chan HLY, Tse CH, Ng YET, Leung KS, Lee KH, Tsui SKW, Sung JJY. Phylogenetic, virologic and clinical characteristics of genotype C hepatitis B with TCC at codon 15 of the precore region. J Clin Microbiol 2006, 44:681-7
  21. Poon TCW, Sung JJY, Chow SM, Ng EKW, Chu ESH, Hui AMY, Leung WK. Diagnosis of gastric cancer by serum proteomic fingerprinting. Gastroenterol 2006, 130:1858-64
  22. Leung WK, Man EPS, Yu J, Go MYY, To KF, Yamaoka YY, Cheng VYY, Ng EKW, Sung JJY. Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in non-cancerous stomach. Clin Cancer Res 2006, 12(10): 3216-21
  23. Tong K, He ML, Lin CK, Guo LP, Kung HF, Sung JJY, Lee SS. The implications of a high allelic frequency of CYP2B6 G516T in ethnic Chinese. Clin Inf Dis 2006, 43:541-2
  24. Poon TCW, Wong N, Lai PBS, Rattray M, Johnson PJ, Sung JJY. A tumor progression model for hepatocellular carcinoma ¡V Bioinformatic analysis of genomic data. Gastroenterology 2006 (In press)

Cancers

Integrated Genome Research

  1. Lui PC, Chau TK, Wong SS, Lau PP, Tse GM, Thomas TM, Ng HK. Cytology of chordoid meningioma: a series of 5 cases with emphasis on differential diagnoses. J Clin Pathol 2006
  2. Tian XX, Zhang YG, Du J, Fang WG, Ng HK, Zheng J. Effects of cotransfection of antisense-EGFR and wild-type PTEN cDNA on human glioblastoma cells. Neuropathology 2006, 26(3): 178-87
  3. Hon SF, Wong GK, Zhu XL, Ng HK, Sin NC, Poon WS. Surgical treatment of a neonate with refractory seizures secondary to congenital giant cell astrocytoma: case report and literature review. Hong Kong Med J 2006, 12(3):222-4
  4. Lee PW, Woo KS, Chow LT, Ng HK, Chan WW, Yu CM, Lo AW. Images in cardiovascular medicine. Diffuse infiltration of lymphoma of the myocardium mimicking clinical hypertrophic cardiomyopathy. Circulation 2006, 113(12):662-4
  5. Baum L, Ng HK, Wong KS, Tomlinson B, Rainer TH, Chen X, Cheung WS, Tang J, Tam WW, Goggins W, Tong CS, Chan DK, Thomas GN, Chook P, Woo KS. Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction. Clin Chem Lab Med 2006, 44(3):274-81
  6. Baum L, Ng HK, Woo KS, Tomlinson B, Rainer TH, Chen X, Cheung WS, Chan DK, Thomas GN, Tong CS, Wong KS. Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk. Clin Biochem 2006, 39(3):191-5. Epub 2006 Feb 9
  7. Pang JC, Chung NY, Chan NH, Poon WS, Thomas T, Ng HK. Rare mutation of PIK3CA in meningiomas. Acta Neuropathol (Berl) 2006, 111(3):284-5. Epub 2006 Feb 7
  8. Chow SC, Ho CY, Tam TT, Wu C, Cheung T, Chan PK, Ng MH, Hui PK, Ng HK, Au DM, Lo AW. Specific epitopes of the structural and hypothetical proteins elicit variable humoral responses in SARS patients. J Clin Pathol 2006, 59(5):468-76. Epub 2006 Feb 3
  9. Chen XY, Lam WW, Ng HK, Fan YH, Wong KS. The frequency and determinants of calcification in intracranial arteries in Chinese patients who underwent computed tomography examinations. Cerebrovasc Dis 2006, 21(1-2):91-7. Epub 2005 Dec 9
  10. Chan WK, To KF, But WM, Lee KW. Frasier syndrome: a rare cause of delayed puberty. Hong Kong Med J 2006, 12(3):225-7
  11. Leung WK, Man EPS, Yu J, Go MYY, To KF, Yamaoka YY, Cheng VYY, Ng EKW, Sung JJY. Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in non-cancerous stomach. Clin Cancer Res 2006, 12(10):3216-21
  12. Leung WK, Chan MC, To KF, man EP, Ng EK, Chu ES, Lau JYW, Lin SR, Sung JJY: H. pylori genotypes and cytokines gene polymorphisms influence the development of gastric intestinal metaplasia in a Chinese population. Am J Gastroenterol 2006, 101(4):714-20
  13. Leong RW, Lawrance IC, Chow DK, To KF, Lau JYW, Wu JCY, Leung WK, Chan FKL, Sung JJY. Association of Intestinal Granulomas with Smoking, Phenotype, and Serology in Chinese Patients with Crohn's Disease. Am J Gastroenterol 2006 May, 101(5):1024-9
  14. Ng WF, To KF, Lam WW, Ng TK, Lee KC. The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1--a review. Hum Pathol 2006, 37(4):381-90. Review
  15. Lam CW, To KF, Tong SF. Genome-wide detection of allelic imbalance in renal cell carcinoma using high-density single-nucleotide polymorphism microarrays. Clin Biochem 2006, 39(3):187-90. Epub 2006 Mar 2
  16. Lee CH, Lau TK, To KF, Lam HS, Chan AW, Ng PC. Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis. Acta Paediatr. 2005 Dec, 94(12):1843-7
  17. Nelson T, To KF, Wong YY, Dickinson J, Choi KC, Yu LM, Ou Y, Chow CB, Wong E ,Tang N, Hjelm M, Chen L. Hong Kong case-control study of sudden unexpected infant deth. NZ Med J. 2005 Dec 16, 118(1227):U1788
  18. Lo AW, Tang NL, To KF. How the SARS coronavirus causes disease: host or organism? J Pathol 2006, 208(2):142-51. Review
  19. Sy SM, Lai PB, Pang E, Wong NL, To KF, Johnson PJ, Wong N. Novel identification of zyxin upregulations in the motile phenotype of hepatocellular carcinoma. Mod Pathol 2006
  20. Wong YF, Sahota DS, Cheung TH, Lo KW, Yim SF, Chung TK, Chang AM, Smith DI. Gene expression pattern associated with radiotherapy sensitivity in cervical cancer. Cancer J 2006, 12(3):189-93
  21. Kwong J, Lee JY, Wong KK, Zhou X, Wong DT, Lo KW, Welch WR, Berkowitz RS, Mok SC. Candidate Tumor-Suppressor Gene DLEC1 Is Frequently Downregulated by Promoter Hypermethylation and Histone Hypoacetylation in Human Epithelial Ovarian Cancer. Neoplasia 2006, 8(4):268-78
  22. Li HM, Man C, Jin Y, Deng W, Yip YL, Feng HC, Cheung YC, Lo KW. Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase. Int J Cancer 2006 May 10
  23. Lo AK, Lo KW, Tsao SW, Wong HL, Hui JW, To KF, Hayward DS, Chui YL, Lau YL, Takada K, Huang DP. Epstein-barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells. Neoplasia. 2006, 8(3):173-80
  24. Wong YF, Cheung TH, Lo KW, Yim SF, Chan LK, Buhard O, Duval A, Chung TK, Hamelin R. Detection of microsatellite instability in endometrial cancer: advantages of a panel of five mononucleotide repeats over the National Cancer Institute panel of markers. Carcinogenesis 2006, 27(5):951-5. Epub 2006 Feb 20
  25. Siu SS, Cheung TH, Lo KW, Yim SF, Chung TK. Is common iliac lymph node dissection necessary in early stage cervical carcinoma? Gynecol Oncol 2006 Feb 18
  26. Wan J, Zhang W, Wu L, Bai T, Zhang M, Lo KW, Chui YL, Cui Y, Tao Q, Yamamoto M, Akira S, Wu Z. BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway. Mol Cell Biol 2006, 26(2):448-56
  27. Wong YF, Cheung TH, Tsao GS, Lo KW, Yim SF, Wang VW, Heung MM, Chan SC, Chan LK, Ho TW, Wong KW, Li C, Guo Y, Chung TK, Smith DI. Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray. Int J Cancer 2006, 118(10):2461-9
  28. Poon TCW, Wong N, Lai PBS, Rattray M, Johnson PJ, Sung JJY. A tumor progression model for hepatocellular carcinoma ¡V Bioinformatic analysis of genomic data. Gastroenterology 2006 (In press)

Cancer Drug Testing

  1. Lee SC, Lim SG, Soo R, Hsieh WS, Guo JY, Putti T, Tao Q, Soong R, Goh BC: Lack of Somatic Mutations in EGFR tyrosine kinase domain in Hepatocellular and Nasopharyngeal Carcinoma. Pharmacogenet Genomics 2006, 16:73-4
  2. Wan J, Zhang W, Wu L, Bai T, Zhang M, Lo KW, Chui YL, Cui Y, Tao Q, Yamamoto M, Akira S, Wu Z: BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway. Mol Cell Biol 2006, 26:448-56
  3. Wong MLY, Tao Q*, Fu L, Wong KY, Qiu GH, FBF Law, Tin PC, Cheung WL, Lee PY, Tang JCO, Tsao GSW, Lam KY, Law S, Wong J, Srivastava G*: (*Corresponding authors) Aberrant promoter hypermethylation and silencing of the critical 3p21 tumor suppressor gene RASSF1A in Chinese esophageal squamous cell carcinoma. Int J Oncol 2006, 28:767-73
  4. Tao Q, Young LS, Woodman CBJ, Murray PG: Epstein-Barr virus (EBV) and its associated human cancers - Genetics, epigenetics, pathobiology and novel therapeutics (Invited review). Front Biosci 2006, 11:2672-713
  5. Ai L, Tao Q, Zhong S, Fields CR, Kim WJ, Lee MW, Cui Y, Brown KD, Robertson KD: Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis 2006, 27:1341-8
  6. Ying J, Li H, Cui Y, Wong AHY, Langford C, Tao Q: Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter. Leukemia 2006, 20:1173-5
  7. Chen YW, Hu X, Liang ACT, Au WY, Wong MLY, Shen L, Tao Q, Chu KM, Kwong YL, Liang R, Srivastava G: High BCL6 expression predicts better prognosis independent of BCL6 translocation status or presence of Ig/BCL6 or non-Ig/BCL6 translocations or BCL6 deregulating mutations in non-coding exon, 1 in gastric lymphoma. Blood 2006; online
  8. Seng TJ, Low JSW, Li HY, Cui Y, Goh HK, Wong MLY, Srivastava G, Sydransky D, Califano J, Steenbergen RDM, Rha SY, Tang J, Hsieh WS, Ambinder R, Tao Q: The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. Oncogene 2006; online
  9. Ying J., Li H.Y., Langford C., Srivastava G., Tsao S.W., Putti T., Murray P., Chan A.T.C., Tao Q.: Functional epigenetics identifies a protocadherin - PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene 2006, 25:1070-80
  10. Baujat B., Audry H., Bourhis J., Chan A.T.C., Onat H., Chua D.T.T., Kwong D.L., Al-sarraf M., Chi K.H., Hareyama M., Leung S.F., Thephamongkhol K., Pignon J.P.: Chemotherapy in locally advanced nasopharynx carcinoma: an individual patient data meta- analysis of eight randomized trials and 1753 patients. Int J Rad Oncol Biol Phys 2006, 64:47-56
  11. Chan S.L., Arifi A.A., Chan A.B., Chan A.T., Ma B.B.: An unusual cause of superior vena cava obstruction. Thorax 2006, 61:182
  12. Teo P.M.L., Leung S.F., Zee B., Lau W.H., Sham J., Lee A.W.M., Tung Y., Au S.K., Chua D., Sze W.M., Leung T.W., Ngan K.C., Kwong D., Law S.C.K., Kwan W.H., Chan A.T.C.: Dose-response relationship of nasopharyngeal carcinoma above conventional tumoricidal level - A study by the Hong Kong nasopharyngeal carcinoma study group (HKNPCSG). Radiat Oncol 2006; 79:27-33
  13. Pang R.T.K., Johnson P.J., Kong E.K.C., Chan A.T.C., Sung J.J.Y., Poon T.C.W: Application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to quantitative proteomic profiling - technical evaluation. Clin Proteomics (In press)
  14. Poon T.C.W., Chow S.M., Ma B.B.Y., Hui E.P., Chan A.T.C. Serum proteomic pattern for predicting recurrence of undifferentiated nasopharyngeal carcinoma after radiotherapy - a potential surrogate marker. Clin Proteomics (In press)
  15. Wong S.C., Chan J.K., Lo E.S., Chan A.K., Wong M.C., Chan C.M., Chan A.T. Breakthrough of immunohistochemistry: The contribution of bifunctional SkipDewax pre-treatment solution, rabbit monoclonal antibodies, and polymer detection systems. Am J Surg Pathol (In press)
  16. Lee A.W.M., Tung S.Y., Chan A.T.C., Chappell R., Fu Y.T., Lu T.X., Tan T., Chua D.T.T., O¡¦Sullivan B., Lu L., Pang E.S.Y., Sze W.M., Leung T.W., Kwan W.H., Chan P.T.M., Liu X.F., Tan E.H., Sham J.S.T., Siu L. and Lau W.H. Preliminary results of a prospective randomized study (NPC-9902 trial) on the therapeutic gain by concurrent chemotherapy and/or accelerated fractionation for locally-advanced nasopharyngeal carcinoma. Int J Rad Oncol Biol Phys (In press)
  17. Ma B.B.Y., King A., Lo Y.M.D., Yau Y.Y., Hui E.P., Zee B., Leung S.F., Kam M.K., Ahuja A., Kwan W.H., Chan A.T.C.: Pre-treatment level of plasma Epstein-Barr virus DNA is an indicator of tumor burden and metabolic activity in nasopharyngeal carcinoma. Int J Rad Oncol Biol Phys (In press)
  18. Yeo W., Boyer M., Chung H.C., Ong S.Y.K., Lim R., Ng E.K.W., Lam K.C., Mo F.K.F., Ho R., Clarke S., Roh J.K., Beale P., Jeung H.C., Rha S.Y., Goh B.C., Zee B., Chan A.T.C.: Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG). Cancer Chem Pharm (In press)
  19. Leung S.F., Zee B., Ma B.Y., Hui E.P., Mo F., Lai M., Chan A.K.C., Chan L.Y.S., Kwan W.H., Lo Y.M.D., Chan A.T.C.: Combined clinical-biomolecular staging for cancer: the model of nasopharyngeal cancer. J Clin Oncol (In press)
  20. Yeo Winnie and Johnson J. Philip: "Diagnosis, Prevention and Management of Hepatitis B Virus Reactivation During Anticancer Therapy". Hepatology 2006, 43(2):209-20
  21. Yeo Winnie, Mo FKF, Koh J, Chan ATC, Leung T, Hui P, Chan L, Tang A, Lee JJ, Mok TST, Lai PBS, Johnson PJ, Zee B: ¡§Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma¡¨. Annals of Oncology 2006, 17: 1083-9
  22. Chen Gong George, Li Mingyue, Lee T. W., Mok Shu Kam Tony and Yim Ping Chuen Anthony: "Induction of Apoptosis by Troglitazone Requires Peroxisome Proliferators-activated Receptor Gamma and ERK in Lung Cancer Cells.". Developmental Biology 2006, 295(1):436
  23. Choi Pui Yu, Yau MEI SZE, Wong Sze Chuen Cesar and Mok Shu Kam Tony: "Effects of Patupilone (Epothilone B; EPO906), A Novel Chemotherapeutic Agent, In Hepatocellular Carcinoma: An In-Vitro Study". American Association for Cancer Research 2006, 47:4734
  24. Chen Gong George, Lee Tak Wai, Yip Hei Yin, Xu Hu, Lee I K Y, Mok Shu Kam Tony, Warner D. Timothy and Yim Ping Chuen Anthony: "Increased Thromboxane B2 Levels are Associated with Lipid Peroxidation and Bcl-2 Expression in Human Lung Carcinoma". Cancer Letters 2006, 236:193-8
  25. Liang Yong, Leung Kwong Sak and Mok Shu Kam Tony: "A Novel Evolutionary Drug Scheduling Model in Cancer Chemotherapy". IEEE Transactions on Information Technology in Biomedicine 2006, 10(2):237-45
  26. Ma Buig Yue Brigette and Chan Anthony Tak Cheung: "Systemic Treatment Strategies and Therapeutic Monitoring for Advanced Nasopharyngeal Carcinoma". Expert review of anticancer therapy 2006, 6(3):383-94
  27. Chan CM*, Ma B, et al: Cyclooxygenase-2 expression in advanced nasopharyngeal carcinoma ¡V a prognostic evaluation and correlation with hypoxia inducible factor 1 and vascular endothelial growth factor * Co-1st author Oral Oncol (Accepted)
  28. Ma B, King A, et al: Pre-treatment level of plasma Epstein Barr Virus DNA and relationship with magnetic resonance delineated tumor volume and [F-18]-fluorodeoxyglucose positron emission tomography uptake in nasopharyngeal carcinoma. Accepted for publication Int J Rad Oncol Bio Phys

Vascular Medicine

  1. Leung HS, Leung FP, Yao X, Ko WH, Chen ZY, Vanhoutte PM, Huang Y: Endothelial mediators of the acetylcholine-induced relaxation of the rat femoral arteries. Vascular Pharmacology 2006, 44(5):299-308
  2. Wong CM, Yao X, Au CL, Tsang SY, Fung KF, Laher I, Vanhoutte PM, Huang Y: Raloxifene prevents endothelial function in aging ovariectomized female rats. Vascular Pharmacology 2006, 44(5):290-8
  3. Lei G, Yeung SYV, Huang Y, Chen ZY: Both soybean and kudzu phytoestrogens modify favorably the blood lipoprotein profile in ovariectomized and castrated hamsters. Journal of Agricultural and Food Chemistry 2006, 54(13):4907-12
  4. Lui K, Borgmeyer U, Huang Y, Suetsugi M, Chen S, Chan FL (2006) Molecular cloning and expression of estrogen receptor-related receptor in rat prostate gland. Prostate (In press)
  5. Leung FP, Tsang SY, Yung LM, Wong CM, Chan YC, Leung HS, Yao X, Huang Y: Raloxifene, tamoxifen and vascular tone. Clinical and Experimental Pharmacology and Physiology 2006
  6. Leung HS, Yung LM, Leung FP, Yao X, Chen ZY, Ko WH, Laher I, Huang Y: Tamoxifen dilates porcine coronary arteries: role of nitric oxide and ouabain sensitive mechanisms. British Journal of Pharmacology 2006
  7. Yung LM, Leung FP, Yao X, Chen ZY, Huang Y: Reactive Oxygen Species in Vascular Wall. Cardiovascular & Haematological Disorders - Drug Targets 2006, 6(1):1-19
  8. Leung HS, Yao X, Leung FP, Ko WH, Chen ZY, Gollasch M, Huang Y: Cilnidipine, a slow-acting Ca2+ channel blocker, induces relaxation in porcine coronary artery: role of endothelial nitric oxide and [Ca2+]i. British Journal of Pharmacology 2006, 147(1):55-63
  9. Zhang R-Z, Yang Q, Yim APC, Huang Y, He G-W: Role of NO and EDHF-mediated endothelial function in the porcine pulmonary circulation: comparison between pulmonary artery and vein. Vascular Pharmacology 2006, 44:183-91
  10. HY Kwan, Y Huang, X Yao: Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G. Journal of Cellular Physiology 2006, 207:315-21
  11. Zhang Q, Fung JW, Auricchio A, Chan JY, Kum LC, Wu LW, Yu CM. Differential Change in Left Ventricular mass and Regional Wall Thickness after Cardiac Resynchronization Therapy for Heart Failure. Eur Heart J 2006, 27:1423-30
  12. Yu CM, Zhang Q, Chan YS, Chan CK, Yip GW, Kum LC, Wu EB, Lee PW, Lam YY, Chan S, Fung JW. Tissue Doppler Velocity is Superior to Displacement and Strain Mapping in Predicting Left Ventricular Reverse Remodeling Response after Cardiac Resynchronization Therapy. Heart 2006, in press (Already published in internet ahead of in print)
  13. PC Leung, KT Cheng, C Liu, WT Cheung, HY Kwan, KL Lau, Y Huang, X Yao: Mechanism of non-capacitative Ca2+ influx in response to bradykinin in vascular endothelial cells. Journal of Vascular Research 2006, 43:367-76
  14. Cheuk-Man Yu, Qing Zhang, Gabriel Wai-Kwok Yip, Yat-Sun Chan, Pui-Wai Lee, Li-Wen Wu,Yat-Yin Lam, Leo Chi-Chiu Kum, Hamish Chi-Kin Chan, Skiva Chan, Jeffrey Wing-Hong Fung. Are Left Ventricular Diastolic Function and Diastolic Asynchrony Important Determinants of Response to Cardiac Resynchronization Therapy? American Journal of Cardiology 2006, in press (Manuscript accepted and scheduled for publication in October 2006)

Diabetes

  1. Kong APS, So WY, Szeto CC, Chan NN, Luk A, Ma RC, Ozaki R, Ng VW, Ho CS, Lam CW, Chow CC, Cockram CS, et al. Assessment of glomerular filtration rate in addition to albuminuria is important in managing type II diabetes. Kidney International 2006, 69:383-7
  2. So WY, Kong APS, Osaki R, Szeto CC, Ma RCW, Chan NN, Ng VWS, Ho CS, Cockram CS, Lam CWK, Chow CC, Cockram CS, et al. Hong Kong Diabetes Registry 2: Glomerular filtration rate, cardiovascular endpoints and all-cause mortality in type 2 diabetic patients. Diabetes Care 2006, 29:2046-52
  3. Cheng AYS, Kong APS, Wong VWS, So WY, Chan HLY, Ho CS, Lam CWK, Tam JS, Chow CC, Cockram CS, Chan JCN, Tong PCY. Chronic hepatitis B viral infection independently predicts renal outcome in type 2 diabetic patients. Diabetologia 2006: May 31 (Epub ahead of print)
  4. Yang XL, Kong APS, So WY, Ma RC, Ho CS, Lam CW, Chow CC, Cockram CS, Tong PC, Chan JC. Effects of chronic hyperglycaemia on incident stroke in Hong Kong Chinese patients with type 2 diabetes. Diabetes/Metabolism Research and Reviews 2006:Jul 27; (Epub ahead of print)
  5. Yang XL, So WY, Kong AP, Clarke P, Ho CS, Lam CW, Ng MH, Lyu RR, Yin DD, Chow CC, Cockram CS, Tong PC, Chan JC. End-stage renal disease risk equations for Hong Kong Chinese patients with type 2 diabetes: Hong Kong Diabetes Registry. Diabetologia 2006:Aug 30 (Epub ahead of print)
  6. Tong PCY, Kong APS, So WY, Ng MHL, Yang XL, Ozaki R, Ma RCY, Lam CWK, Ho CS, Chow CC, Cockram CS, Chan JCN. Hematocrit, Independent of chronic kidney disease, predicts adverse cardiovascular outcomes In Chinese patients with type 2 diabetes mellitus. Diabetes Care 2006: in press
  7. So WY, Ma RC, Ozaki R, Tong PC, Ng MC, Ho CS, Lam CW, Chow CC, Chan WB, Kong APS, Chan JCN. Angiotensin-converting enzyme (ACE) inhibition in type 2, diabetic patients-- interaction with ACE insertion/ deletion polymorphism. Kidney International 2006, 69:1438-43
  8. Ozaki R, Qiao Q, Wong GWK, Chan MHM, So WY, Tong PCY, Ho CS, Ko GTC, Kong APS, Lam CWK, Tuomilehto J, Chan JCN. The relationship between attendance at schools of low academic achievements and the risk for metabolic syndrome in Hong Kong Chinese Adolescents. Archives for Pediatrics and Adolescent Medicine, 2006 in press
  9. Ng VWS, Kong APS, Choi KC, Ozaki R, Wong GWK, So WY, Tong, PCY, Sung R, Xu S, Ho CS, Lam CWK, Chan JCN. Body mass index and waist circumference as predictors for cardiovascular risk factor clustering among adolescents using receiver operating characteristic analysis. Obesity Research 2006 in press

Regenerative Medicine

  1. Ko CH, Yung E, Li K, Li CL, Ng PC, Fung KP, Wong RP, Chui KM, Gu GJ, Fok TF. Multiplex primer extension reaction screening and oxidative challenge of glucose-6-phosphate dehydrogenase mutants in hemizygous and heterozygous subjects. Blood Cells Mol Dis 2006 Jun 13. [Epub ahead of print]
  2. Li K, Sung RY, Huang WZ, Yang M, Pong NH, Lee SM, Chan WY, Zhao H, To MY, Fok TF, Li CK, Wong YO, Ng PC. Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin. Circulation 2006, 113(18):2211-20
  3. Ng PC, Li K, Leung TF, Wong RP, Li G, Chui KM, Wong E, Cheng FW, Fok TF. Early prediction of sepsis-induced disseminated intravascular coagulation with interleukin-10, interleukin-6, and RANTES in preterm infants. Clin Chem 2006, 52(6):1181-9
  4. Suen PM, Li K, Chan JC, Leung PS. In vivo treatment with glucagon-like peptide 1 promotes the graft function of fetal islet-like cell clusters in transplanted mice. Int J Biochem Cell Biol 2006, 38(5-6):951-60
  5. Li K, Chuen CK, Lee SM, Law P, Fok TF, Ng PC, Li CK, Wong D, Merzouk A, Salari H, Gu GJ, Yuen PM. Small peptide analogue of SDF-1alpha supports survival of cord blood CD34+ cells in synergy with other cytokines and enhances their ex vivo expansion and engraftment into nonobese diabetic/severe combined immunodeficient mice. Stem Cells 2006, 24(1):55-64
  6. Ng PC, Li G, Chui KM, Chu WC, Li K, Wong RP, Fok TF. Quantitative measurement of monocyte HLA-DR expression in the identification of early-onset neonatal infection. Biol Neonate 2006, 89(2):75-81
  7. Senok AC, Nelson EAS, Li K, Ismaeel ARY, Olliaro P, Oppenheimer SJ. Ultrastructural assessment of Plasmodium falciparum in age-fractionated thalassaemic erythrocytes. Parasitol Res 2006, 98:381-4

Public Health

  1. Griffiths S, Hunter DJ: New Perspectives in Public Health, Radcliffe Publishing Ltd, 2006
  2. Griffiths S: The role of postgraduate medical education and training board. Arch Dis Child 2006; 91: 195-7
  3. Yu H, Jing H, Chen Z, Zheng H, Zhu X, Wang H, Wang S, Liu L, Zu R, Luo L, Xiang N, Liu H, Liu X, Shu Y, Lee SS, Chuang SK, Wang Y, Xu J, Yang W; Streptococcus suis study groups: Human streptococcus suis infection outbreak, Sichuan, China. Emerg Infect Dis 2006; 12: 914-20
  4. Lee SS, Lee KC, Wan WY, Wong KH: A urine-based approach to scale up HIV testing in drug users. AIDS 2006; 20: 1439-51
  5. Tong K, He ML, Lin CK, Guo LP, Kung HF, Sung JJY, Lee SS: The implications of a high allelic frequency of CYP2B6 G516T in ethnic Chinese. Clin Inf Dis 2006; 43: 541-2
  6. Tu SP, Cui JT, Liston P, Huajiang X, Xu R, Lin MC, Zhu YB, Zou B, Ng SS, Jiang SH, Xia HH, Wong WM, Chan AO, Yuen MF, Lam SK, Kung HF, Wong BC: Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant.?Gastroenterology 2005; 128: 361-75
  7. Wong QN, Ng VC, Lin MC, Kung HF, Chan D, Huang JD: Efficient and seamless DNA recombineering using a thymidylate synthase A selection system in Escherichia coli.?Nucleic Acids Res 2005; 33: e59
  8. Wang J, Peng Y, Sun YW, He H,Zhu S, An X, Li M, Lin MC, Zou B, Xia HH, Jiang B, Chan AO, Yuen MF, Kung HF, Wong BC: All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer. Gastroenterology 2006; 130: 747-58
  9. Li M, Ng SMS, Wang JD, Lai LH, Leung SY, Franco M, Peng Y, He ML, Kung HF, and Lin CMM.: EFA6A enhances glioma cell invasion through ARF6/ERK signaling. Cancer Res 2006; 66: 1583-90
  10. Rachlin J, Ding C, Cantor C, Kasif S: MuPlex: multi-objective multiplex PCR assay design. Nucleic Acids Res 2005; 33: W544-7
  11. McCullough RM, Cantor CR, Ding C: High-throughput alternative splicing quantification by primer extension and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Nucleic Acids Res 2005; 33: e99
  12. Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB: MONaKA, a novel modulator of the plasma membrane Na,K-ATPase.? J Neurosci 2005; 25: 7934-43
  13. Chim SS, Tong YK, Chiu RW, Lau TK, Leung TN, Chan LY, Oudejans CB, Ding C, Lo YM: Detection of the placental epigenetic signature of the maspin gene in maternal plasma. Proc Natl Acad Sci USA 2005; 102: 14753-8
  14. Ding C, Lo YM: MALDI-TOF mass spectrometry for quantitative, specific and sensitive analysis of DNA and RNA. Ann N Y Acad Sci 2006; 1075: 282-7
  15. Zhang M, Rosenberg PS, Brown DL, Preiss L, Konkle BA, Eyster ME, Goedert JJ; Second Multicenter Hemophilia Cohort Study: Correlates of spontaneous clearance of hepatitis C virus among people with hemophilia. Blood 2006; 107: 892-7
  16. Yu IT, Chiu YL, Au JS, Wong TW, Tang JL: Dose-response relationship between cooking fumes exposures and lung cancer among Chinese nonsmoking women.? Cancer Res 2006; 66: 4961-7
  17. Wong TW, Tam W, Yu IT, Wun YT, Wong AH and Wong CM: Association between air pollution and general practitioner visits for respiratory diseases in Hong Kong.? Thorax 2006; 61: 585-91
  18. Tse LA, Yu IT: Letters to the Editor, Re: ¡§Occupational risk factors for esophageal and stomach cancers among female textile workers in Shanghai, China¡¨. Am J Epidemiol 2006; 164: 402
  19. Tang JL: Research priorities in traditional Chinese medicine. BMJ 2006; 333: 391-4
  20. Zhang XH, Guan TR, Mao JW, Liu LS: Economic development and stroke mortality in Chinese populations between 1987 and 2000.? Stroke 2006; 37: 720

Epithelial Cell Biology

  1. Chen J, Ng CP, Rowlands DK, Xu PH, Gao JY, Chung YW, Chan HC, Interaction between enteric epithelial cells and Peyer's patch lymphocytes in response to Shigella lipopolysaccharide: Effect on nitric oxide and IL-6 release. World J Gastroenterol 2006, 12(24):3895-900
  2. Zhu JX, Zhang GH, Yang N, Connie Wong HY, Chung YW, Chan HC, Involvement of intracellular and extracellular Ca2+ in tetramethylpyrazine-induced colonic anion secretion. Cell Biol Int 2006, 30(6):547-52. Epub 2006 Mar 22
  3. Chan HC, Shi QX, Zhou CX, Wang XF, Xu WM, Chen WY, Chen AJ, Ni Y, Yuan YY, Critical role of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Mol Cell Endocrinol 2006, 250(1-2):106-13. Epub 2006 Jan 18

Proteomics

  1. Poon TC: Opportunities and limitations of SELDI-TOF-MS in biomedical research: practical advices. Expert Rev Proteomics 2007; 4: 51-65
  2. Poon TCW, Wong N, Lai PBS, Rattray M, Johnson PJ, Sung JJY: A tumor progression model for hepatocellular carcinoma ¡V Bioinformatic analysis of genomic data. Gastroenterology 2006; 131: 1262-70
  3. Poon TC, Chiu CH, Lai PB, Mok TS, Zee B, Chan AT, Sung JJ, Johnson PJ: Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma. World J Gastroenterol 2005; 11: 6701-6
  4. Ang IL, Poon TC, Lai PB, Chan AT, Ngai SM, Hui AY, Johnson PJ, Sung JJ: Study of serum haptoglobin and its glycoforms in the diagnosis of hepatocellular carcinoma ¡V a glycoproteomic approach. J Proteome Res 2006; 5: 2691-700
  5. Sung FL, Pang RT, Ma BB, Lee MM, Chow SM, Poon TC, Chan AT: Pharmacoproteomics study of cetuximab in nasopharyngeal carcinoma. J Proteome Res 2006; 5: 3260-7
  6. Poon TCW, Sung JJY, Chow SM, Ng EKW, Yu ACW, Chu ESH, Hui AAY, Leung WK: Diagnosis of gastric cancer by serum proteomic fingerprinting. Gastroenterology 2006; 130: 1858-64
  7. Pang RTK, Poon TCW, Chan KCA, Lee NLS, Chiu RWK, Tong YK, Chim SSC, Sung JJY, Lo YMD: Serum amyloid A is not useful in the diagnosis of severe acute respiratory syndrome. Clin Chem 2006; 52: 1202-4
  8. Pang RT, Poon TC, Chan KCA, Lee NL, Chiu RWK, Tong YK, Wong RM, Chim SSC, Ngai SM, Sung JJ, Lo YMD: Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome. Clin Chem 2006; 52: 421-9
  9. Kam RK, Poon TC, Chan HL, Wong N, Hui AY, Sung JJ: High-throughput quantitative profiling of serum N-Glycome by MALDI-TOF mass spectrometry and N-Glycomic fingerprint of liver fibrosis. Clin Chem 2007 May 17; (Epub ahead of print PMID: 17510303)

Emerging Infectious Diseases

  1. Sung JJY, Chan HLY: HBV-ISS (Dynavax) Curr Opin Mol Ther 2006; 8: 150-5
  2. Chan MH, Chan PK, Griffith JF, Chan IH, Lit LC, Wong CK, Antonio GE, Liu EY, Hui DS, Suen MW, Ahuja AT, Sung JJY, Lam CW: Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy. Pathology 2006; 38: 229-35
  3. Yu CM, Wong RS, Wu EB, Kong SL, Wong J, Yip GW, Soo YO, Chiu ML, Chan YS, Hui D, Lee N, Wu A, Leung CB, Sung JJY: Cardiovascular complications of severe acute respiratory syndrome. Postgrad Med J 2006; 82: 140-4
  4. Roccia F, Agrati C, Castilletti C, Bordi L, Gioia C, Horejsh D, Ippolito G, Chan PK, Hui DS, Sung JJY Capobianchi MR, Malkovsky M: Anti-severe acute respiratory syndrome coronavirus immune responses: the role played by V gamma 9V delta 2 T cells. J Infect Dis 2006; 193: 1244-9
  5. Pang RT, Poon TC, Chan KC, Lee NL, Chiu RW, Tong YK, Wong RM, Chim SS, Ngai SM, Sung JJY, Lo YMD: Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome. Clin Chem 2006; 38: 229-35
  6. Wang J, He H, Yu L, Xia HH, Lin MC, Gu Q, Li M, Zhou B, An X, Jiang B Kung HF, Wong BC: Heat shock factor 1 (HSF1) downregulates X-linked inhibitor of apoptosis protein-associated factor 1 (XAF1) through transcriptional regulation. J Biol Chem 2006; 281: 2451-9
  7. Li XP, Li CY, Li X, Ding Y, Chan LL, Yang PH, Li G, Liu X, Lin JS, Wang J, He M, Kung HF, Lin MC, Peng Y: Inhibition of human nasopharyngeal carcinoma growth and metastasis in mice by adenovirus-associated virus mediated expression of human endostatin. Mol Cancer Ther 2006; 5: 1290-8
  8. He ML, Lin C, Tong K, Xu B, Sung JJY, Kung HF, Lee SS: Absence of CYP2B6 promoter -82T>C mutation in Chinese as an additional factor for slow metabolism of drugs commonly used in infections. Eur J Clin Pharmacol 2006; 62: 585-6
  9. Li X, Liu X, Li CY, Ding Y, Chau D, Li G, Kung HF, Lin MC, Peng Y: Recombination adeno-associated virus (rAAV) mediated RNA interference inhibits metastasis of nasopharyngeal cancer cells in vivo and in vitro by suppression of Epstein-Barr virus encoded LMP-1. Int J Oncol 2006; 29: 595-603
  10. Qiao CF, Han QB, Song JZ, Mo SF, Kong LD, Kung HF, Xua HX: Quality assessment of fructus psoraleae. Chem Pharm Bull (Tokyo) 2006; 54: 887-90
  11. Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR: Functional interactions of Raf and MEK with jun-N-Terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway. Biochemistry 2006; 44: 10784-95
  12. Peng Y, Yang PH, Tanner JA, Huang JD, Li M, Lee HF, Xu RH, Kung HF, Lin MC: Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis. Biochem Biophys Res Commun 2006; 344: 416-24
  13. Li M, Ng SSM, Wang JD, Lai LH, Leung SY, Franco M, Peng Y, He ML, Kung HF, and Lin CMM: EFA6A enhances glioma cell invasion through ARF6/ERK signaling. Cancer Res 2006; 66: 1583-90
  14. Huo LF, Tang JW, Huang JJ, Huang PT, Huang CF, Kung HF, Lin MC: Cancer immunotherapy targeting the telomerase reverse transcriptase. Cell Mol Immunol 2006; 3: 1-11
  15. Tong K, He ML, Lin CK, Guo LP, Kung HF, Sung JJY, Lee SS: The implications of a high allelic frequency of CYP2B6 G516T in ethnic Chinese. Clin Infect Dis 2006; 43: 541-2
  16. He ML, Zheng BJ, Chen Y, Wong KL, Huang JD, Lin MC, Peng Y, Yuen KY, Sung JJY, Kung HF: Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus. FEBS Let 2006; 580: 2414-20
  17. Luo C, Peng Y, Santti R, He ML, Lin MC: COX-1 and -2 expressions in sex-related organs of neonatally estrogen-treated rats and in activated and nonactivated macrophage RAW264.7 cells with phytoestrogen. Endocrine 2006; 29: 161-76