KO Ho, Owen
Name : KO Ho, Owen 高浩
Title :
Clinical lecturer
Home Department :  Medicine and Therapeutics
Email :
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Academic training

2012 – 15             Bachelor of Medicine and Bachelor of Surgery (MBChB), The Chinese University of Hong Kong (CUHK)

2008 – 12             PhD in Neuroscience, University College London (UCL)

2007 – 08             Intercalated Bachelor of Medical Sciences (BMedSc, 1st Class), CUHK

2005 – 07             Pre-clinical medicine, CUHK


Academic appointments

2016 – present     Clinical Lecturer, Department of Medicine and Therapeutics, Faculty of Medicine, CUHK

2013 – 15             Honorary Research Associate, Department of Medicine and Therapeutics, Faculty of Medicine, CUHK

2011 – 12             Postdoctoral Researcher, Department of Neuroscience, Physiology and Pharmacology, UCL


Specialised Research Area(s):

Systems Neuroscience; Neural Circuitry; Neurovascular Biology


Selected Publications:

1. Li Q, Ko H (joint-1st author), Qian ZM, Yan L, Chan DCW, Arbuthnot G, Ke Y, WH Yung, “Refinement of learned skilled movement representation in motor cortex deep output layer”, manuscript under revision

2. Okun M, Steinmetz N, Cossell L, Iacaruso MF, Ko H, Barthó P, Moore T, Hofer SB, Mrsic-Flogel TD, Carandini M, Harris KD, “Diverse coupling of neurons to populations in sensory cortex”, Nature, 2015 Apr 6. doi: 10.1038/nature14273

3. Cossell L, Iacaruso MF, Muir DR, Houlton R, Sader EN, Ko H, Hofer SB, Mrsic-Flogel TD, “Functional organization of excitatory synaptic strength in primary visual cortex”, Nature, 2015 Feb 19;518(7539):399-403.

4. Ko H, “Functional organization of synaptic connectivity in the neocortex”, Runner-up essay, Eppendorf and Science Prize for Neurobiology 2014, Science, 2014 Oct 31; 346(6209):555.

5. Huang Y, Yoon K, Ko H, Jiao S, Ito W, Wu JY, Yung WH, Lu B, Morozov A, “5-HT3a receptors modulate hippocampal gamma oscillations by regulating synchrony of parvalbumin-positive interneurons”, Cerebral Cortex, 2014 Sep 21. pii: bhu209

6. Ko H, Mrsic-Flogel TD, Hofer SB, “Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience”, The Journal of Neuroscience, 2014 Jul 16;34(29):9812-6.

7. Ko H, Cossell L, Baragli C, Antolik J, Clopath C, Hofer SB, Mrsic-Flogel TD, “The emergence of functional microcircuits in visual cortex”, Nature, 2013 Apr 4;496(7443):96-100.

8. Li Q, Ke Y, Chan DCW, Qian ZM, Yung KKL, Ko H, Arbuthnott GW, Yung WH, “Therapeutic deep brain stimulation in parkinsonian rats directly influences motor cortex”, Neuron, 2012 Dec 6;76(5):1030-41.

9. Hofer SB, Ko H (joint-1st author), Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD, “Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex”, Nature Neuroscience, 2011 Jul 17;14(8):1045-52.

10. Ko H, Hofer SB, Pichler B, Buchanan KA, Sjöström PJ, Mrsic-Flogel TD, “Functional specificity of local synaptic connections in neocortical networks”, Nature, 2011 May 5;473(7345):87-91.