Research
TSE, Gary
Name : Gary Tse
Title :
Assistant Professor
Home Department :  Department of Medicine and Therapeutics
Email : Tseg@cuhk.edu.hk
Website :
http://www.mect.cuhk.edu.hk/people/garytse.html
Personal Website:  https://sites.google.com/site/garytse86/

Biography:

Qualifications

2017                   M.P.H. (Public Health Medicine), The University of Manchester, United Kingdom

2015                   Ph.D. (Cardiac Electrophysiology), The University of Cambridge, United Kingdom

2014                   M.B.B.S. (Clinical Medicine), Imperial College London, United Kingdom

2012                   M.A., The University of Cambridge, United Kingdom

2008                   B.A. Hons. (Pre-clinical Medicine), The University of Cambridge, United Kingdom

Academic Appointments

2016                   Assistant Professor (Clinical), Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong

2015                   Assistant Professor, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong

Professional Memberships and Fellowships

- Fellow, European Society of Cardiology (FESC) (2016)

- Chartered Scientist, The Science Council (CSci) (2016)

- Fellow, Institute of Biomedical Sciences (FIBMS) (2016)

- Fellow, Royal Society of Public Health (FRSPH) (2016)

- Fellow, Linnean Society of London (FLS) (2014)

- Fellow, Cambridge Philosophical Society (FCPS) (2009)

- Member, Royal Society of Medicine (2005)

 

Specialised Research Area(s):

Pre-clinical and clinical cardiac electrophysiology; Inflammation and endothelial dysfunction in cardio-metabolic disorders; Stem cell and cardiovascular regeneration; Epidemiology of cardiovascular diseases.

 

Selected Publications:

1. Fu, H., Li, G., Liu, C., Li, J., Cheng, L., Yang, W., Tse, G., Zhao, J., Liu, T. (2016) Probucol prevents atrial ion channel remodeling in an alloxan-induced diabetes rabbit model. Oncotarget. PMID: 27863381. DOI: 10.18632/oncotarget.13339.

2. Tse, G.*, Liu, T., Li, K.H., Laxton, V., Chan, Y.W., Keung, W., Li, R.A., Yan, B.P. (2016) Electrophysiological mechanisms of Brugada syndrome: insights from pre-clinical and clinical studies. Frontiers in Physiology. 7:467. PMID: 27803673. DOI: 10.3389/fphys.2016.00467.

3. Tse, G.* (2016) (Tpeak-Tend)/QRS and (Tpeak-Tend)/(QT x QRS): novel markers for predicting arrhythmic risk in the Brugada syndrome. Europace. pii: euw194. PMID: 27707783. DOI: 10.1093/europace/euw194.

4. Tse, G.*, Yan, B.P. (2016) Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death. Europace. pii: euw280. PMID: 27702850. DOI: 10.1093/europace/euw280.

5. Tse, G.*, Yeo, J.M., Tse, V., Kwan, J., Sun, B. (2016) Gap junction inhibition by heptanol increases ventricular arrhythmogenicity by decreasing conduction velocity without affecting repolarization properties or myocardial refractoriness in Langendorff-perfused mouse hearts. Molecular Medicine Reports. 14(5):4069-4074.  PMID: 27633494. DOI: 10.3892/mmr.2016.5738.

6. Chen, Z., Sun, B., Tse, G., Jiang, J., Xu, W. (2016) Reversibility of both sinus node dysfunction and reduced HCN4 mRNA expression level in an atrial tachycardia pacing model of tachycardia-bradycardia syndrome in rabbit hearts. International Journal of Clinical and Experimental Pathology. 9:8526-8531.

7. Choy, L., Yeo, J.M., Tse, V., Chan, S.P., Tse, G.* (2016) Cardiac disease and arrhythmogenesis: mechanistic insights from mouse studies. International Journal of Cardiology Heart & Vasculature. 12:1-10. PMID: 27766308. DOI: 10.1016/j.ijcha.2016.05.005.

8. Tse, G.*, Yan, B.P., Chan, Y.W., Tian, XY., Huang, Y. (2016) Reactive oxygen species, endoplasmic reticulum stress and mitochondrial dysfunction: the link with cardiac arrhythmogenesis. Frontiers in Physiology. 7:313. PMID: 27536244. DOI: 10.3389/fphys.2016.00313.

9. Tse, G.*, Lai, E.T., Tse, V., Yeo, J.M. (2016) Molecular and electrophysiological mechanisms underlying cardiac arrhythmogenesis in diabetes mellitus. Journal of Diabetes Research. 2016:2848759. PMID: 27642609. DOI: 10.1155/2016/2848759.

10. Tse, G.*, Wong, S.T., Tse, V., Yeo, J.M. (2016) Depolarization vs. repolarization: what is the mechanism of ventricular arrhythmogenesis underlying sodium channel haploinsufficiency in mouse hearts? Acta Physiologica (Oxford). PMID: 27084434. DOI: 10.1111/apha.12694.

11. Tse, G.*, Wong, S.T., Tse, V., Lee, Y.T., Lin, H.Y., Yeo, J.M. (2016) Cardiac dynamics: alternans and arrhythmogenesis. Journal of Arrhythmia: 32(5):411-417. PMID: 27761166. DOI: 10.1016/j.joa.2016.02.009.

12. Tse, G., Tse, V., Yeo, J.M., Sun, B. (2016) Atrial anti-arrhythmic effects of heptanol in Langendorff-perfused mouse hearts. PLoS ONE. 11(2):e0148858. PMID: 26872148. DOI: 10.1371/journal.pone.0148858.