CHEUNG, Wing Hoi Louis

Name : CHEUNG, Wing Hoi Louis 張穎愷
Title :
Professor (non-clinical)
Graduate Division Head, Department of Orthopaedics and Traumatology
Deputy Director, Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology
Home Department :  Orthopaedics and Traumatology
Email :
Phone Number: 
(852) 3505 2715
Room 74047, 5/F, Lee Chee Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong
Website :


Wing Hoi Cheung is a Professor in the Department of Orthopaedics & Traumatology, Head of the Graduate Division, and Deputy Director of the Musculoskeletal Laboratory. He also assumes the role of Deputy Director for the MSc program in Musculoskeletal Medicine, Rehabilitation, and Geriatric Orthopaedics at CUHK. Meanwhile, he holds courtesy researcher positions at CUHK Shenzhen Research Institute and the Hong Kong-Shenzhen Innovation and Technology Research Institute (FITRI).

After earning his PhD from the Department of Orthopaedics & Traumatology at CUHK in 2000, Professor Cheung joined the university's academic staff in 2005. His work has been recognized with prestigious awards such as AO Berton Rahn Research Fund Prize, Beijing Municipal Science and Technology Award First Prize and 10th HOMA Academic Achievement Award in Osteoporosis Medical Research in recent years. Professor Cheung serves as a grant reviewer for prominent organizations, Associate Editor and Editorial board member in many international scientific journals. With over 150 peer-reviewed international articles, 9 book chapters, more than 360 conference abstracts, and one book (as editor) to his credit, Professor Cheung's research has made a significant impact on the field of orthopaedics. He also holds 4 patents (including 1 PCT and 3 US/China patents), reflecting his commitment to translating research into practical applications.

Specialised Research Area(s):

  • Pathogenesis and treatment of sarcopenia, osteoporosis and osteoporotic fracture healing
  • Mechanical stimulation for treating musculoskeletal ageing problems

Selected Publications:

1. Long YF, Chow SK, Cui C, Wong RMY, Zhang N, Qin L, Law SW, Cheung WH. Does exercise influence skeletal muscle by modulating mitochondrial functions via regulating MicroRNAs? A systematic review. Ageing Res Rev. 91:102048, 2023.

2. Li J, Leung SSY, Chung YL, Chow SKH, Alt V, Rupp M, Brochhausen C, Chui CS, Ip M, Cheung WH, Wong RMY. Hydrogel delivery of DNase I and liposomal vancomycin to eradicate fracture-related methicillin-resistant staphylococcus aureus infection and support osteoporotic fracture healing. Acta Biomater. 164:223-239, 2023.

3. Liu C, Wong PY, Chung YL, Chow SKH, Cheung WH, Law SW, Chan JCN, Wong RMY. Deciphering the ‘obesity paradox’ in the elderly: a systematic review and meta-analysis of sarcopenic obesity. Obes Rev. e13534, 2022.

4. Chow SK, Wong CH, Cui C, Li MM, Wong RMY, Cheung WH. Modulating macrophage polarization for the enhancement of fracture healing, a systematic review. J Orthop Translat. 36:83-90, 2022.

5. Cheung WH, Hung VWY, Cheuk KY, Chau WW, Tsoi KKF, Wong RMY, Chow SKH, Lam TP, Yung PSH, Law SW, Qin L. Best performance parameters of HR-pQCT to predict fragility fracture – systematic review and meta-analysis. J Bone Miner Res. 36(12):2381-2398, 2021.

6. Cheng KYK, Chow SKH, Hung VWY, Wong CHW, Wong RMY, Tsang CSL, Kwok T, Cheung WH. Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis (BIA) validated with DXA. J Cachexia Sarcopenia Muscle. 21(6):2163-2173, 2021. 

7. Chui CS, Leung KS, Qin JH, Shi DF, Augat P, Wong RMY, Chow SKH, Huang XY, Chen CY, Lai YX, Yung PSH, Qin L, Cheung WH. Population-based and personalized design of total knee replacement prosthesis for additive manufacturing based on Chinese anthropometric data. Engineering. 7(3):386-94, 2021.

8. Wang J, Cui C, Chim YN, Yao H, Shi L, Xu J, Wang J, Wong RMY, Leung KS, Chow SKH, Cheung WH. Vibration and HMB suppresses intramuscular fat infiltration and adipogenic differentiation in sarcopenic mice. J Cachexia Sarcopenia Muscle. 11:564-77, 2020.

9. Choy MHV, Wong RMY, Li MC, Wang BY, Liu XD, Lee W, Cheng JCY, Chow SKH, Cheung WH. Can we enhance osteoporotic metaphyseal fracture healing through enhancing ultra-structural and functional changes of osteocytes in cortical bone with low-magnitude high-frequency vibration? FASEB J. 34(3):4234-4252, 2020. 

10. Qin JH, Chow SK, Guo AY, Wong WN, Leung KS, Cheung WH. Low magnitude high frequency vibration accelerated cartilage degeneration but improved epiphyseal bone formation in anterior cruciate ligament transection induced osteoarthritis rat model. Osteoarthritis Cartilage. 27(7):1061-7, 2014.