Biography:

Dr. Bei Huang is a research assistant professor of the Department of Psychiatry at The Chinese University of Hong Kong. She graduated with honours from Suzhou Medical College, Soochow University in 2014 and completed her postgraduate training in Neurology from the Naval Medical University, Shanghai, in 2017. Before joining CUHK psychiatry in April 2021 as postdoctoral fellow, Dr. Huang has obtained her PhD degree in Medical Sciences from the Faculty of Medicine CUHK in Jan 2021.

Dr. Huang’s current research interests are primarily focus on understanding the epidemiology, pathophysiology, and diagnosis of neurodegenerative diseases and sleep disorders especially REM sleep behavior disorder. In particular, she is actively working on the gut-brain hypothesis of Parkinson’s disease, targeting gut microbiota, host-gut microbiota interactions, inflammatory pathways, as well as the development of novel gut-based diagnostic tools and therapeutics for the early identification and prevention of Parkinson's disease and other neurodegenerative disorders.

Specialised Research Area(s):

• Gut microbiome dysbiosis in neurodegenerative diseases
• Pathophysiology of REM sleep behavior disorder
• Microbiota-targeted interventions, especially next-generation probiotics development
  
• Gastrointestinal disorder and neurodegeneration

1. Huang B, Chau SWH, Liu Y, Chan JWY, Wang J, Zhang J, Ma SL, Chan PKS, Yeoh, YK, Chen Z, Wong, SH, Mok VCT, To KF, Lai HM, Ng S, Trenkwalder C, Chan FKL, Wing YK. Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives. Nat Commun. 2023 May 2;14(1):2501. 

2. Wang J, Lam SP, Huang B, Liu Y, Zhang J, Yu MWM, Tsang JCC, Zhou L, Chau SWH, Chan NY, Chan JWY, Schenck CH, Li SX, Mok VCT, Ma KKY, Chan AYY, Wing YK. Familial α-synucleinopathy spectrum features in patients with psychiatric REM sleep behaviour disorder. J Neurol Neurosurg Psychiatry. 2023 Nov;94(11):893-903.

3. Zhou L, Li SX, Chau SW, Huang B, Wang J, Tang S, Chan JW, Zhang J, Yu MW, Tsang JC, Hu MT, Mok VC, Wing YK, Liu Y. Altered Impulsivity Across Drug-Naïve Parkinsonism, Isolated Rapid Eye Movement Sleep Behavior Disorder, and Their High-Risk Relatives. Ann Neurol. 2023 Nov 23. 

4. Huang B, Zhang J, Wang J, Chau SWH, Chan JWY, Yu MWM, Li SX, Zhou L, Mok V, Wing YK, Liu Y. Isolated dream-enactment behaviours as a prodromal hallmark of rapid eye movement sleep behaviour disorder. J Sleep Res. 2023 Jun;32(3):e13791.

5. Lin Y, Huang B, Zhou L, Wang J, Tang S, Chau SWH, Chan JWY, Liu Y, Wing YK. The association of nocturnal enuresis with autonomic dysfunctions, mood disturbances, and sleepwalking in isolated rapid eye movement sleep behavior disorder. Sleep. 2023 Jul 11;46(7):zsad062.

6. Zhou L, Chau SWH, Liu Y, Wang J, Zhang J, Chan NY, Chan JWY, Huang B, Chen S, Li SX, Mok VCT, Wing YK. Personality profile and its association with conversion to neurodegenerative disorders in idiopathic REM sleep behavior disorder. NPJ Parkinsons Dis. 2022 Jul 14;8(1):91.

7. Wang J, Chau SWH, Lam SP, Liu Y, Zhang J, Chan NY, Cheung MMS, Yu MWM, Tsang J, Chan JWY, Huang B, Li SX, Mok VCT, Wing YK. Prevalence and correlates of REM sleep behaviour disorder in patients with major depressive disorder: a two-phase study. J Neurol Neurosurg Psychiatry. Sep 2022;93(9):1010-1017.

8. Liu Y, Zhang J, Chau SWH, Yu MWM, Chan NY, Chan JWY, Li SX, Huang B, Wang J, Feng H, Zhou L, Mok VCT, Wing YK. Evolution of Prodromal REM Sleep Behavior Disorder to Neurodegeneration: A Retrospective, Longitudinal Case-control Study. Neurology. Aug 9 2022;99(6):e627-e637. *

9. Huang B, Xu T, Wang Z, Chen K, Zhang J, Zhao Z, Zhuang J, Wu H. The Clinical Characteristics of Cataplectic Attack in Narcolepsy Type 1. Sleep Med. Jan 2021;77:261-269.

10. Feng H, Chen L, Liu Y, Chen X, Wang J, Yu MWM, Huang B, Li SY, Chau SWH, Chan JWY, Chen J, Mok VCT, Wing YK, Zhang JH. Rest-Activity Pattern Alterations in Idiopathic REM Sleep Behavior Disorder. Annals of Neurology. 2020;88(4):817-29.