• Epidemiology, Diagnosis and Management of Heart Failure and Valvular Heart Disease
• Device and Technique Innovation in Structural Heart Interventions
• Cardiogenic Shock and Mechanical Circulatory Support
• Application of Big Data Analysis and Artificial Intelligence in Structural Heart Disease and Heart Failure

Kent So specializes in minimally invasive treatments for structural and valvular heart disease. His team’s research spans translational studies, epidemiology, imaging, interventional techniques, and device innovation to improve outcomes.

Key areas include epidemiology of valvular diseases in the Asia-Pacific, novel diagnostics and management for heart failure and valvular disease, device and technique innovation, and use of big data and artificial intelligence. His work emphasizes safety, expanding indications, and strategies for complex interventions. The group seeks biomarkers and investigates pathogenesis of aortic valve and mitral annular calcification to develop therapeutic targets that prevent or slow valve degeneration and improve patient care.

Kent So graduated from the Faculty of Medicine at The Chinese University of Hong Kong with an MBChB degree. He was awarded the prestigious Sir David Todd Scholarship, which supported his advanced fellowship training in structural heart interventions at Henry Ford Hospital in Detroit, USA.

Currently, Kent serves as Clinical Assistant Professor in the Department of Medicine and Therapeutics at The Chinese University of Hong Kong and Director of Structural Heart Interventions at Prince of Wales Hospital.

His achievements include the Cardiovascular Business Forty Under Forty Award (USA, 2025), the Shanghai Technology Advancement Award 2023 (First Class) for device innovation in left atrial appendage occlusion, and the Outstanding Team Award from the Hospital Authority (2023). He is widely recognised as a leader in transcatheter valvular and structural heart interventions in the Asia-Pacific region. He serves as Co-Director of the Asia Pacific Congenital and Structural Heart Intervention Symposium (APCASH) 2025 and CSI-Asia Pacific 2025, and holds leadership roles including Vice President of the Hong Kong Society of Congenital and Structural Heart Disease.

Kent has authored over 100 peer-reviewed in high-impact journals such as JACC: Cardiovascular Interventions, JACC Asia, Circulation: Cardiovascular Interventions, JAMA Cardiology, and European Journal of Heart Failure. He currently serves as Associate Editor of JACC: Case Reports. As a global physician proctor, he has supervised numerous structural heart procedures, including TAVI/TAVR, mitral and tricuspid edge-to-edge repair (M-TEER/T-TEER), transcatheter tricuspid valve replacement (TTVR), and left atrial appendage occlusion (LAAO).

His clinical and research interests focus on the epidemiology, diagnosis, and management of heart failure and valvular heart disease, device and technique innovation in structural heart interventions, cardiogenic shock and mechanical circulatory support, and the application of big data analysis and artificial intelligence in structural heart disease and heart failure.

1. 40 Under 40 Award, Cardiovascular Business, USA (2025)
2. First Class Award (上海市科學技術進步獎一等獎), Shanghai People’s Government (2024)
3. Outstanding Team Award (Multidisciplinary Complex Coronary Revascularization Team), Hospital Authority, Hong Kong (2023)
4. Sir David Todd Memorial Scholarship, Hong Kong College of Physicians (2019)
5. Mr and Mrs Law Chung Wan Prize for Distinction in Medicine, The Chinese University of Hong Kong (2009)

1. Salter B, Tang GHL, Hahn RT, Lala A, Adams DH, Asgar A, Borger MA, Fam NP, Ho EC, Khera S, Kini AS, Latib A, Lee APW, Lerakis S, Lurz P, Safi LM, Sorajja P, Stephan von Bardeleben R, Praz F, O’Gara PT, Wong HMK, Wong RHL, Zaid S, So KCY. A contemporary look at the landscape of treatment of tricuspid regurgitation: A review. JAMA Cardiology. Published online January 14, 2026. doi:10.1001/jamacardio.2025.4337.
2. Wong LN, Chan HT, Chan TH, Hui WH, Lai LKL, Kam KKH, Chow SCY, Lee APW, So KCY. Platypnea-orthodeoxia syndrome after transcatheter aortic valve implantation. Circulation-Cardiovascular Imaging. 2026;19(1):18495. doi:10.1161/circimaging.125.018495.
3. So KC, Meemook K, Xu J, Chang C, Ngernsritrakul T, Leelasithorn S, Lee C, Lai A, Kam KK, Yan BP, Lee AP, Sung ASH, Lam Y. Initial real-world experience of tricuspid transcatheter edge-to-edge repair in Asia. JACC: Asia. 2026;6(1):16-23. doi:10.1016/j.jacasi.2025.07.024.
4. Chan VHT, Meemook K, Lee CW, Lai A, Chang CC, Ngernsritrakul T, Leelasithorn S, Kam KKH, Yan BP, Lee APW, Tang GHL, Lam YY, Sung ASH, So KCY. Features and short-term outcomes of real-world transcatheter tricuspid valve repair vs. replacement in Asia-Pacific. Annals of Cardiothoracic Surgery. 2026;15(2):21-21. doi:10.21037/acs-2025-aw-45-tvd.
5. Shek J, Wong MCK, Chan VHT, Fong FK, Wong GLN, Kam KKH, Lee APW, So KCY. “Bridging to plug” for an A3-scallop prolapse with deficient posterior leaflet. JACC Cardiovascular Interventions. 2025;18(14):1817-1819. doi:10.1016/j.jcin.2025.05.020. (Editorial)
6. Fong FK, Wong GLN, Chow SCY, Kam KKH, Lee APW, So KC. Sandwiching the flying clip: Lux transcatheter tricuspid valve replacement for TriClip single leaflet device attachment. JACC Cardiovascular Interventions. 2025;18(10):1345-1347. doi:10.1016/j.jcin.2025.02.015.
7. Stolz L, Fam N, Ong G, Villablanca P, Jabri A, de Backer O, Mølller JE, Tchétché D, Oliva O, So KCY, Lam YY, Latib A, Ho EC, Scotti A, Coisne A, Sudre A, Dreyfus J, Nejjari M, Cruz-Gonzalez I, Estévez-Loureiro R, Barreiro-Perez M, Leurent G, Donal E, Bonnet G, Modine T, Makkar R, Patel D, Kresoja KP, Lurz P, Hausleiter J. Transcatheter tricuspid valve replacement using the LuX-Valve plus system: 1-year compassionate use outcomes. European Journal of Heart Failure. 2025;27(11):2644-2648. doi:10.1002/ejhf.70010.
8. So KC, Walters D, Meemook K, Xu J, Lai A, Chang C, Ngernsritrakul T, Leelasithorn S, Thaw KM, Murdoch D, Lee C, Kam KK, Scalia G, Yan BP, Lee AP, Tang GHL, Lam Y, Sung ASH. Single TriClip steerable guide for combined MitraClip and TriClip transcatheter edge-to-edge repair (STriC-TEER): A multicenter experience. Circulation-Cardiovascular Interventions. 2025;18(12):e015864. doi:10.1161/circinterventions.125.015864.
9. Tam MTK, Kojodjojo P, Lam YY, Chow J, Wong C, Kam KKH, Wong GLN, Chan CP, Chan JYS, So KC. Combined pulsed field ablation and left atrial appendage occlusion: A multicenter comparative study. Heart Rhythm. 2025;22(10):2579-2584. doi:10.1016/j.hrthm.2025.03.1968.
10. So KC, Xu J, Kam KK ho, Sung SH, Meemook K, Wang DD, Tang GHL, Lee AP, Lam Y. Current status of tricuspid valve interventions in Asia Pacific region. JACC: Asia. 2025;5(3):405-423. doi:10.1016/j.jacasi.2024.10.008.
11. So KC, Yap J, Song G, Poon K, Sung SH, Chandavimol M, Hayashida K, Park DW, Ewe SH, Chen M, Chan VH, Iwata J, Tangcharoen T, Tern P, Park HS, Alasnag M, Ohno Y, Hon JKF, Bhagwandeen R, Tabata M, Lee AP, Jilaihawi H, Wang DD, Tang GHL, Lim DS, Modine T, Lam Y. Epidemiology of valvular heart disease in Asia Pacific region. JACC: Asia. 2025;5(6):718-743. doi:10.1016/j.jacasi.2025.03.011.
12. So KC, Stolz L, Fam N, Ong G, Cheung A, Boone R, Villablanca P, Jabri A, Lam Y, Tchétché D, Oliva O, de Backer O, Mølller JE, Latib A, Scotti A, Coisne A, Sudre A, Dreyfus J, Nejjari M, Favre PE, Cruz-Gonzalez I, Estévez-Loureiro R, Barreiro-Perez M, Makkar R, Patel D, Leurent G, Donal E, Modine T, Hausleiter J. Transjugular transcatheter tricuspid valve replacement in patients with cardiac implantable electronic devices. JACC: Asia. 2025;5(10):1260-1269. doi:10.1016/j.jacasi.2025.07.009.
13. So KC, Kam KK, Tang GHL, Lee APW. Feasibility of using TriClip guide for combined MitraClip and TriClip transcatheter edge-to-edge repair: First-in-human experience. JACC Cardiovascular Interventions. 2024;17(8):1071-1072. doi:10.1016/j.jcin.2024.02.024. (Letter)
14. Lai LKL, So C, Chui K, Kam KK, Kwok KW, Wong RHL, Cheung GSH, Lam Y, Lee AP. Plug and clip: Percutaneous repair of a perforated mitral valve complicating severe functional mitral regurgitation. JACC Cardiovascular Interventions. 2022;15(4):e41-e43. doi:10.1016/j.jcin.2021.12.009.
15. So CY, Li S, Fu GH, Chen W, Kam KKH, Lee APW, Chu HM, Xu YW, Yan BP, Lam YY. Procedural and short-term outcomes of occluding large left atrial appendages with the LAmbre device. 2021;17(1):90-92. doi:10.4244/eij-d-19-00821.
16. So CY, Kang G, Villablanca PA, Ignatius A, Asghar S, Dhillon D, Lee JC, Khan A, Singh G, Frisoli TM, O’neill BP, Eng MH, Song T, Pantelic M, O’neill WW, Wang DD. Additive value of preprocedural computed tomography planning versus stand-alone transesophageal echocardiogram guidance to left atrial appendage occlusion: Comparison of real-world practice. Journal of the American Heart Association. 2021;10(17):20615. doi:10.1161/jaha.120.020615.
17. So CY, Fan Y, Wu EB, Lee APW. Anticipating coronary obstruction with three-dimensional printing in transcatheter aortic valve implantation. 2020;14(16):1424-1425. doi:10.4244/eij-d-19-00609.
18. So C, Leung K, Lam Y, Yan BP. Occlusion of an extremely large left atrial appendage using the “double-LAmbre technique.” JACC Cardiovascular Interventions. 2019;12(11):1085-1087. doi:10.1016/j.jcin.2018.10.015.
19. So C, Lam Y, Cheung GS, Chan CKY, Chen S, Chan AK, Park J, Schmidt B, Yan BP. Minimalistic approach to left atrial appendage occlusion using the LAmbre device. JACC Cardiovascular Interventions. 2018;11(11):1113-1114. doi:10.1016/j.jcin.2018.01.275.
20. So KCY, Fan Y, Sze L, Kwok K, Chan AK, Cheung GSH, Lee APW. Using multimaterial 3-dimensional printing for personalized planning of complex structural heart disease intervention. JACC Cardiovascular Interventions. 2017;10(11):e97-e98. doi:10.1016/j.jcin.2017.02.045.