• Advanced Diagnosis, Prevention and Treatment of Bone Metabolic Disorders, especially Osteoporosis and Osteonecrosis, and Healing Enhancement of Musculoskeletal Injuries, in Collaboration with Research and Clinical Scientists in Medicine, Geriatrics, Rheumatologists, Traditional Medicine, and Biomaterials
• Musculoskeletal Imaging, especially in Bone Densitometry, Histomorphometry and Skeletal Biomechanics

• Musculoskeletal Disorders, including Osteoporosis, Osteonecrosis and Osteoarthritis
• Musculoskeletal Injury and Repair, including Fracture and Tendon-Bone Insertion Repair
• Innovation, Research and Development of Biodegradable Metals for Orthopaedic Applications

Ling Qin is Professor and Director of SIAT-HKU-CUHK Joint Laboratory for Innovative Biomaterials in the Department of Orthopaedics & Traumatology, the Chinese University of Hong Kong (https://www.ort.cuhk.edu.hk). Ling also holds joint professorship in Shenzhen Institutes of Advance Technology (SIAT) of Chinese Academy of Sciences (CAS) and serves Director of the Translational Medicine Research & Development Center of Institute of Biomedical & Health Engineering of SIAT (http://www.siat.cas.cn). He received his BA and M.Phil. in basic medical and life sciences in physical education at the Beijing Sports University in China, and his PhD from German Sports University, Cologne, Germany and postdoctoral training in AO-Research Institute, Davos, Switzerland, and Doctor Honoris Causa of Semmelweis University of Hungary. Professor Qin was research scientist in the Department of Trauma & Reconstructive Surgery, University Clinic Rudolf Virchow, Charite Medical University in Germany before joining CUHK in late 1994.

Ling is the past President of the International Chinese Musculoskeletal Research Society (ICMRS) (http://www.icmrs.net) and member of a number of journal editorial boards, such as Editor-in-chief of Journal of Orthopaedic Translation (http://www.e-jot.com). He holds memberships in several international and national orthopaedic and related research organizations, including member of Academy of Europe (MAE) (https://www.ae-info.org) and fellow of American Institute of Medical and Biological Engineering (AIMBE) (http://www.aimbe.org). He has received over 40 Research Awards and holds over 40 innovation or new utility patents from PR China and USA.

Ling published 10 monographs as editor or associate editor, 5 conference proceedings, 80 book chapters, and over 540 journal papers in English, German, and Chinese, including around 500 SCI articles published in Nature Medicine, Advanced Materials, Materials Today, JCI, Nature Communications, ARD, JBMR, with total citations over 39,000, H-index 104. He is listed as World’s top 2% Scientist (Stanford University rating) and World’s Best Medicine Scientists in Research.com (https://research.com).

1. Honorary Doctorate, Semmelweis University (2025)
2. Distinguished Translational Research Investigator Award, International Chinese Musculoskeletal Research Society (ICMRS) (2025)
3. Frontier Explorer, Shenzhen Futian District Committee of the Communist Party of China, Shenzhen Futian District People’s Government (2025)
4. 廣東省生物醫藥健康促進會科技獎「創新成果獎」一等獎, 廣東省生物醫藥健康促進會 (2025)
5. Geneva International Invention Gold Medal with Jury Congratulations, Geneva International Exhibition (2025)
6. International Invention Fair in the Middle East Gold Medal, Kuwait Science Club (2025)
7. 中國生物材料學會「科學技術獎」一等獎, 中國生物材料學會 (2023)
8. Benton Rahn Achievement Award, AO Foundation (2020)
9. 「中國專利獎」銀獎, 國家知識產權局 (2020)
10. 「中華醫學科技獎」二等獎, 中華醫學會 (2018)

1. Gong M, Zha Y, Lu S, Zhang T, Wang X, Liu L, Fan C, Zeng H, Wang D, Song T, Wang J, Wu Y, Zhang M, Lai Y, Qin L, Jiang X. Efficacy and safety of the low-temperature-derived 3D printed biodegradable Mg-containing composite porous scaffold for bone defect repair: A prospective and multi-center randomized controlled trial. Biomaterials. 2026;327:123751. doi:10.1016/j.biomaterials.2025.123751.
2. Hegyi P, Garami A, Solymosi K, Morsanyi K, Kuppuswamy A, Wenning AS, Vancsa S, Varga G, Teutsch B, Rancz A, Obeidat M, Nagy R, Harnos A, Farkas R, Engh MA, Barna V, Zumla A, Zaidi M, Yu J, Yazici H, Agusti A, et al. Academia europaea’s guidelines for the visualization of clinical outcomes. Nature Medicine. 2025;31(12):3976-3980. doi:10.1038/s41591-025-03992-1. (Editorial)
3. Guo J, Yao H, Chang L, Zhu W, Zhang Y, Li X, Yang B, Dai B, Chen X, Lei L, Chen Z, Li Y, Zheng L, Liu W, Tong W, Su Y, Qin L, Xu J. Magnesium nanocomposite hydrogel reverses the pathologies to enhance mandible regeneration. Advanced Materials. 2025;37(2). doi:10.1002/adma.202312920.
4. Zhu Y, Dai B, Zhang S, Liu J, Xu S, Liu W, Chen X, Zhang H, Li Q, Pang FOS, Li W, Wen C, Qin L, Xu J, Ngai T. Tissue mimetic membranes for healing augmentation of tendon-bone interface in rotator cuff repair. Advanced Materials. 2025;37(10). doi:10.1002/adma.202407358.
5. An Y, Zhang H, Zhang S, Zhang Y, Zheng L, Chen X, Tong W, Xu J, Qin L. Degradation products of magnesium implant synergistically enhance bone regeneration: Unraveling the roles of hydrogen gas and alkaline environment. Bioactive Materials. 2025;46:331-346. doi:10.1016/j.bioactmat.2024.12.020.
6. Shao H, Xu S, Zeng F, Jin Z, Ji X, Shan Z, Kang J, Tian Q, Zhang S, Mao Z, Zhang Y, Xu J, Tong W, Qin L. Metal-organic framework-integrated nanoplatform orchestrates osteochondral-synovial homeostasis for osteoarthritis therapy. ACS Nano. 2025;19(36):32744-32766. doi:10.1021/acsnano.5c10692.
7. An Y, Zheng L, Zhang S, Zhang H, Zhang Y, Shao H, Tong W, Chen Z, Yao H, Wen Z, Xu S, Li Y, Tian Q, Cheng L, Sun W, Qin L, Xu J. Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis. Biomaterials. 2025;323:123428. doi:10.1016/j.biomaterials.2025.123428.
8. Zhang H, Chen X, Ong MTY, Lei L, Zheng L, Dai B, Tong W, Fu BSC, Xu J, Yung PSH, Qin L. Current advances of artificial ligaments for anterior cruciate ligament reconstruction: From biocompatibility to bioactivity. Engineering. 2025;46:47-59. doi:10.1016/j.eng.2024.10.018. (Review)
9. Zu H, Zheng L, Huo M, Liu K, Halling Dreyer C, Zhang Y, He X, Li Y, Zou L, Huang L, Yi X, Sun AR, Meng X, Shi K, Cao H, Zu X, Tong W, Hokiu Chow D, Wang X, Lai Y, Xu J, Ding M, Lu J, Qin L. Tree-inspired magnesium hybrid column for preventing hip collapse in steroid-associated osteonecrosis in bipedal emus. Materials Today. 2024;80:113-138. doi:10.1016/j.mattod.2024.08.009.
10. Xu S, Zhang Y, Dai B, Rao J, Deng F, Zhang S, Shao H, Li X, Jin Z, Liang T, Yang Y, Li Y, Chen Z, Tong W, Xu J, Ning C, Qin L. Green-prepared magnesium silicate sprays enhance the repair of burn-skin wound and appendages regeneration in rats and minipigs. Advanced Functional Materials. 2024;34(9). doi:10.1002/adfm.202307439.
11. He X, Li Y, Miao H, Xu J, Ong MT yun, Wang C, Zheng L, Wang J, Huang L, Zu H, Yao Z, Mi J, Dai B, Li X, Yung PS hang, Yuan G, Qin L. High formability Mg-Zn-Gd wire facilitates ACL reconstruction via its swift degradation to accelerate intra-tunnel endochondral ossification. Journal of Magnesium and Alloys. 2024;12(1):295-315. doi:10.1016/j.jma.2022.12.006.
12. Li X, Liang T, Dai B, Chang L, Zhang Y, Hu S, Guo J, Xu S, Zheng L, Yao H, Lian H, Nie Y, Li Y, He X, Yao Z, Tong W, Wang X, Chow DHK, Xu J, Qin L. Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment. Journal of Clinical Investigation. 2024;134(10). doi:10.1172/jci166795.
13. Zheng N, Xu J, Ruan YC, Chang L, Wang X, Yao H, Wang J, Zhang R, Xue Q, Tang N, Ong T yun, Schilcher J, O’Keefe RJ, Qin L. Magnesium facilitates the healing of atypical femoral fractures: A single-cell transcriptomic study. Materials Today. 2022;52:43-62. doi:10.1016/j.mattod.2021.11.028.
14. Dai B, Xu J, Li X, Huang L, Hopkins C, Wang H, Yao H, Mi J, Zheng L, Wang J, Tong W, Chow DH kiu, Li Y, He X, Hu P, Chen Z, Zu H, Li Y, Yao Y, Jiang Q, Qin L. Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis. Nature Communications. 2022;13(1):427-. doi:10.1038/s41467-021-27683-w.
15. Mi J, Xu JK, Yao Z, Yao H, Li Y, He X, Dai BY, Zou L, Tong WX, Zhang XT, Hu PJ, Ruan YC, Tang N, Guo X, Zhao J, He JF, Qin L. Implantable electrical stimulation at dorsal root ganglions accelerates osteoporotic fracture healing via calcitonin gene-related peptide. Advanced Science. 2022;9(1). doi:10.1002/advs.202103005.
16. Ye Li, Xu J, Mi J, He X, Pan Q, Zheng L, Zu H, Chen Z, Dai B, Li X, Pang Q, Zou L, Zhou L, Huang L, Tong W, Li G, Qin L. Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis. Biomaterials. 2021;275:120984. doi:10.1016/j.biomaterials.2021.120984.
17. Tian L, Sheng Y, Huang L, Chow DHK, Chau WH, Tang N, Ngai T, Wu C, Lu J, Qin L. An innovative Mg/Ti hybrid fixation system developed for fracture fixation and healing enhancement at load-bearing skeletal site. Biomaterials. 2018;180:173-183. doi:10.1016/j.biomaterials.2018.07.018.
18. Zhang Y, Xu J, Ruan YC, Yu MK, O’Laughlin M, Wise H, Chen D, Tian L, Shi D, Wang J, Chen S, Feng JQ, Chow DHK, Xie X, Zheng L, Huang L, Huang S, Leung K, Lu N, Zhao L, Li H, Zhao D, Guo X, Chan K, Witte F, Chan HC, Zheng Y, Qin L. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine. 2016;22(10):1160-1169. doi:10.1038/nm.4162.
19. Zhao D, Huang S, Lu F, Wang B, Yang L, Qin L, Yang K, Li Y, Li W, Wang W, Tian S, Zhang X, Gao W, Wang Z, Zhang Y, Xie X, Wang J, Li J. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head. Biomaterials. 2016;81:84-92. doi:10.1016/j.biomaterials.2015.11.038.
20. Zhang G, Guo B, Wu H, Tang T, Zhang BT, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D, Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L, Qin L. A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nature Medicine. 2012;18(2):307-314. doi:10.1038/nm.2617.